wordpress gives “Error establishing a database connection” inVPS server

I read all answers like my question on stack, but I didn’t find what I need.

I have no problems with “wp-config” file. All is working not normally, till i rebooting VPS. Site working normally for 10-15 minutes after reboot. Then again friert.
I got this error from “wp-admin” in my site:

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Error establishing a database connection This either means that the
username and password information in your wp-config.php file is
incorrect or we can’t contact the database server at localhost. This
could mean your host’s database server is down.

Are you sure you have the correct username and password? Are you sure
that you have typed the correct hostname? Are you sure that the
database server is running? If you’re unsure what these terms mean you
should probably contact your host. If you still need help you can
always visit the WordPress Support Forums.
please who can help?
I am ready to answer all questions

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